World Journal of Pharmaceutical Research
STUDY ON ANTIMICROBIAL ACTIVITY OF ZINC AND COPPERNANOPARTICLES
ABSTRACT
The aim of this study was to investigate the antimicrobial activity of ZnO and CuO nanoparticles on bacteria Gram-negative (Escherichia coli) Gram-positive bacteria (Bacillus) and fungi Aspergillus and Penicillium. Test method Well diffusion agar is used. Results, showed antimicrobial properties by inhibiting growth of bacterial strains by Zinc nanoparticles on Bacillus (0.7mm), E-coli (1.2mm) and fungal strains on Aspergillus(1.3mm), Penicillium(1.1mm). Inhibiting growth of bacterial strains by Copper nanoparticles on Bacillus (0.5mm), Ecoli (0.8mm) and fungal strains on Aspergillus(0.8mm), Penicillium(0.7mm). It was observed that Zinc nanoparticles have more inhibition on E.Coli and Aspergillus than Copper nanoparticles so Zinc nanoparticles have more antimicrobial activity than copper nanoparticles.
KEYWORDS: Antimicrobial, Bacillus E-coli, Aspergillus, Penicillium, ZnO nanoparticles, CuO nanoparticles, Inhibition.
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